Aging and human longevity. Volume 1. Edited by O. N. Tkacheva
Synopsis
The book Aging and Human Longevity edited by O.N. Tkacheva was authored by leading Russian gerontologists and geriatricians. It synthesizes both global and Russian advancements in the study of aging.
The monograph is composed of two volumes, which systematically investigate the phenomenon of aging and human longevity.
Volume 1 focuses on a range of general concepts related to gerontology. The historical overview and the analysis of demographic aspects of aging are supplemented with a discussion of rare phenomena, such as longevity and progeria. The book provides a comprehensive overview of available approaches for biological age estimation and offers a systematic analysis of existing theories of aging. Of particular note is the chapter that addresses geroprotective technologies, which investigates non-pharmacological strategies and the geroprotective potential of pharmacological agents. The authors evaluated the prospects of gene therapy and regenerative medicine, offering a well-balanced view of their application.
Volume 2 discusses the phenomenon of organ and system aging. The text describes age-related changes in the immune, nervous, endocrine, cardiovascular, and other systems. It emphasizes the pathophysiological mechanisms and clinical symptoms of aging.
The book provides an analysis of the most recent advancements in gerontology and a critical review of the controversial hypotheses of aging and geroprotection, which encourages further scientific research. The text targets a broad audience, ranging from biologists and clinicians (e.g., general practitioners, cardiologists, neurologists) to students and researchers. This research will be of particular benefit to specialists who study aging, such as gerontologists and geriatricians.
Edited by
Olga N. Tkacheva, Dr. Sci. (Med.), Professor, Corresponding Member of the Russian Academy of Sciences; Director, Russian Research and Clinical Center of Gerontology, Pirogov Russian National Research Medical University of the Russian Ministry of Health; Department Chairman, Department of Age-Related Diseases, Institute of Continuing Education and Professional Development, Faculty of Additional Professional Education, Pirogov Russian National Research Medical University of the Russian Ministry of Health; Chief Freelance Specialist of the Russian Ministry of Health in Geriatrics
Reviewers:
Michael A. Piradov, Ph.D. Med.; Professor, Academician of the Russian Academy of Sciences, President of the Research Center of Neurology, Vice-President of the Russian Academy of Sciences; https://orcid.org/0000-0002-6338-0392
Alexander G. Rumyantsev, Ph.D. Med.; Professor, Academician of the Russian Academy of Sciences, Director of the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology; https://orcid.org/0000-0002-1643-5960
Chapters
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Preface
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List of Abbreviations
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Introduction
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Chapter 1. Increase in Life Expectancy and Population Aging in the 20–21 centuries
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Chapter 2. History of Gerontology
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Chapter 3. Centenarians
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Chapter 4. Premature Aging Syndromes
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Chapter 5. Theories and Mechanisms of Aging
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Chapter 6. Biological Age Estimation
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Chapter 7. Relationship Between Physical Activity and Aging Rates
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Chapter 8. Nutrition and Aging
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Chapter 9. Physical Methods of Geroprotection
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Chapter 10. Prevention of Brain Aging and Age-Related Cognitive Decline
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Chapter 11. Sleep and Aging
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Chapter 12. Effect of Psychoemotional Stress on Aging Rates
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Chapter 13. Relationship Between Smoking and Aging Rates
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Chapter 14. Geroprotective Effects of Blood Donation
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Chapter 15. Vitamin D and Aging
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Chapter 16. Geroprotectors: from Biological Basis to Clinical Perspectives
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Chapter 17. Сomplementary Medicine in Geroprotection
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Chapter 18. Psychotherapeutic Counseling for Elderly
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Chapter 19. Gene Therapy of Age-Related Processes and Diseases
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Chapter 20. Regenerative Medicine and Aging
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Appendix 1. Current clinical studies of potential geroprotectors
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Appendix 2. The Interventions Testing Program (ITP) of the National Institute on Aging (NIA)
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